Do lipids tune B cell signaling?

Iztok Urbančič, Christian Eggeling, Erdinc Sezgin
Nature Chemical Biology, March 2023; doi: 10.1038/s41589-023-01303-8 (read more here).


The role of lipid membrane domains in the activation of immune cells remains elusive. New microscopy data on B cell signaling support a mechanism in which lipid membrane domains consolidate upon B cell receptor clustering.