Two-photon retinal theranostics by adaptive compact laser source

Rok Podlipec, Jaka Mur, Jaka Petelin, Janez Štrancar, Rok Petkovšek
Applied Physics A, May 2020; doi: 10.1007/s00339-020-03587-2 (read more here).

In brief

In our work, compact fiber-laser based on high-speed gain-switched laser diode has been shown to achieve adaptable/independently tunable repetition rate and energy per pulse allowing coupled fluorescence lifetime ophthalmic diagnostics via two-photon excitation and phototherapy via laser-induced photodisruption on a local molecular environment in a complex ex vivo retinal tissue.